CBD conversion to THC with Ultrasonic bath

[Dr. MMX]

Beautiful idea

 

[Eleusius_hive_reboot]

I LOVE YOUR ETHICS !...feels good to make the experience of like-mindedness.... lets
show that we are not a bunch of degenerate thugs.... its the best counteract to the
authorities,being MORE professional and especially care more about the recipients health, of our

Products, than the corrupt big pharma industry..., (nice 4-methylmethcathinone-hydrochloride ....by the way, looks almost analytical grade)

 

[Dr. MMX]

Everybody has its job in the world

 

[rotovap5002]

This gives d8 not d9.

 

[William D.]

You are talking about synthesis without ultrasound. In which we get almost pure d8. Here we get a mixture.

 

[William D.]

Now remind the old Shulgin condensation (and others) from olivetol. What acid was used there to obtain d9? Yes, pTSA. You will obtain d8 almost pure without the use of ultrasound. Because with a more time, the d9 in the reaction undergoes isomerization to d8. This is the meaning of ultrasound synthesis. A shorter reaction time that allows you to keep this process to some extent.

 

[Rabidreject]

Hey am I meant to be vacuum distilling what I obtain before eating it?

 

[Rabidreject]

Okay. I ran one reaction at room temp with 3% p-tsa in DCM for 24h.
A second reaction was run with no solvent at elevated temps. I melted the CBD on a hot plate, chucked in the 3% p-tsa and let it stir for an hour. This was then dissolved in DCM.
They were both worked up in the same manner - water wash, bicarbonate washes, brine wash, dried over MgSO4 and solvent removed.

I have two oils. The higher temperature one is around 2.7g and is a sort of red colour, whilst the second one (unweighed as of yet but it looks like more oil for sure) is noticeably lighter in colour.

I will bioassay each of them once, see if there is any differences and then make more and this time do enough to bother with vacuum distilling it after.

 

[William D.]

5% pTSA
48hours for RT synth
You can add a little more acid, your stirring should be good if you do the RT synthesis.

 

[Rabidreject]

Oh that’s interesting. Ok so I didn’t use enough acid and I didn’t let it go long enough. Nice 1
Yeah I did have stirring on full as well

 

[Rabidreject]

oh also they were 5g scale reactions! Whoops

 

[Rabidreject]

Also I spilled a lot.

it worked though, is def active. Will make more so that vacuum distilling is more worthwhile.

 

[Rabidreject]

I will say. It’s a super annoying substance to do chemistry with.
Makes cleaning really annoying - or more so than anything iv done in the past and it’s just generally pretty annoying to handle.
I ended up doing a 20g reaction of this, I just need to distil it now but again, it’s an annoying task for me to do coz the noise.

 

[William D.]

The noise is really a terrible thing, I want to run away. Where there is something good, always burrow the pig