Hello,
After many tests using Methylamine HCL based on this method I will share the best way that I found to obtain Methamphetamine freebase in big scale:
- Fill the reactor with the 14 L of Methanol
- With stirring dissolve the Methylamine HCL
- Put the reactor temp at 0C(not the mixture temp) and add the NaOH, the temp will increase
- Once the temp come back to 20C add the P2P, the temp will increase stir it during 45min-1 hour
- Add 252gr of anhydrous sodium sulfate
- When the mixture temp arrives to 8C start adding portionwise the NaBH4 not exceeding the 20C
- Once all the NaBH4 has been added let it mixing under 20C during aprox 2 hours until the mixture stops bubbling
- Add the water and continue mixing during 5 min
- Add the DCM and mix it during 10 min
- Stop stirring and let layers get separated
- Keep the bottom layer and discard the upper one( not profitable to extract this aqueous phase)
- Add 200gr of anhydrous sodium sulfate to the saved layer and mix it
- Filter it in Buchner Funnel
- Evaporate the DCM
- Clean and smelly Methamphetamine freebase obtained
;-)
After many tests using Methylamine HCL based on this method I will share the best way that I found to obtain Methamphetamine freebase in big scale:
- 966 gr P2P
- 14 liters Methanol
- 1183 gr Methylamine HCL
- 638gr NaOH
- 452 gr Anhydrous Sodium Sulfate
- 105 gr NaBH4
- 35 L distilled water
- 7 Liters DCM
- Fill the reactor with the 14 L of Methanol
- With stirring dissolve the Methylamine HCL
- Put the reactor temp at 0C(not the mixture temp) and add the NaOH, the temp will increase
- Once the temp come back to 20C add the P2P, the temp will increase stir it during 45min-1 hour
- Add 252gr of anhydrous sodium sulfate
- When the mixture temp arrives to 8C start adding portionwise the NaBH4 not exceeding the 20C
- Once all the NaBH4 has been added let it mixing under 20C during aprox 2 hours until the mixture stops bubbling
- Add the water and continue mixing during 5 min
- Add the DCM and mix it during 10 min
- Stop stirring and let layers get separated
- Keep the bottom layer and discard the upper one( not profitable to extract this aqueous phase)
- Add 200gr of anhydrous sodium sulfate to the saved layer and mix it
- Filter it in Buchner Funnel
- Evaporate the DCM
- Clean and smelly Methamphetamine freebase obtained
;-)
↑View previous replies…
- By magdagessler
Have anybody ever tried to reduce tha amounts of solvent. Did anybody have some experience how it infuence on yield??
- By Xiao hua
How to make ice rock crystal ? Can you make a video.
↑View previous replies…
- By btcboss2022
Of course you could filter it but the methylamine odor in big scale is too much disgusting to take it out from reactor and filter it.
In my case I don't filter anything in that process.
In my case I don't filter anything in that process.
- By Akashic
@btcboss2022 When drying your schiff base, with addition of NaSO4 onward, are you leaving it in there throughout the reduction?
ive wondered about this awhile now, if it’s okay to do this without side reactions, in this particular application could silica beads good alternative?
In @G.Patton Tech I believe it’s directed to filter and wash drying agent before boro addition in MeOH, also read elsewhere to use toluene to prevent quenching with NaBH4 and that this method doesn’t work well P2P and it’s best use is with MDP2P
Any thought or suggestions anyone?
ive wondered about this awhile now, if it’s okay to do this without side reactions, in this particular application could silica beads good alternative?
In @G.Patton Tech I believe it’s directed to filter and wash drying agent before boro addition in MeOH, also read elsewhere to use toluene to prevent quenching with NaBH4 and that this method doesn’t work well P2P and it’s best use is with MDP2P
Any thought or suggestions anyone?
- By btcboss2022
Of course you could filter it but the methylamine odor in big scale is too much disgusting to take it out from reactor and filter it.
In my case I don't filter anything in that process.
In my case I don't filter anything in that process.
- By hunter12
Do you vacuum distill your oil freebase before crystallisation?
↑View previous replies…
- By wael gano
Welcome
I wonder what your way to meth is
Note that I have now made a small amount of nitrous oxide and p2np
So what path to take I am confused in the good crop but from what
Are you using aluminum amalgam with p2p and methylamine hydrochloride with hitting sodium hydroxide to produce methyl base on site? Are things looking okay?
What do you use in your Likert reaction? Have you tried the yield from it?
I wonder what your way to meth is
Note that I have now made a small amount of nitrous oxide and p2np
So what path to take I am confused in the good crop but from what
Are you using aluminum amalgam with p2p and methylamine hydrochloride with hitting sodium hydroxide to produce methyl base on site? Are things looking okay?
What do you use in your Likert reaction? Have you tried the yield from it?
- By btcboss2022
Seriously?! The only answer I can think after reading this is 
How is possible that someone could ask this questions precisely in the post where the process is detailed?! It's unbelievable.
The truth that does not cease to surprise me but it seems to me a lack of attention even I would say that respect for others but well let's leave it here I prefer no go deeper on it.
How is possible that someone could ask this questions precisely in the post where the process is detailed?! It's unbelievable.
The truth that does not cease to surprise me but it seems to me a lack of attention even I would say that respect for others but well let's leave it here I prefer no go deeper on it.
