1-Fenyyli-2-nitropropeenin (P2NP) videosynteesi bentsaldehydistä ja nitroetaanista. Henryn reaktio.

[HIGGS BOSSON]

Nitroetaaniin liittyvät ongelmat alkoivat Euroopassa jo vuonna 2007, minkä jälkeen vähitellen kaikki maat asettivat rajoituksia tälle arvokkaalle reagenssille. Ja nyt on kaksi tapaa: etsiä toimittajia maista, joissa on heikko lainsäädäntö ja kehittynyt kemianteollisuus, esimerkiksi Bangladeshista, tai syntetisoida itsenäisesti, mihin me olemme ehdottaneet menetelmää.

 

[Alojz]

Millä voidaan korvata tai syntetisoida nitroetaani?

 

[Kvadprime]

You can find methods of syntes nitroethane in another thread

 

[Kvadprime]

I have aniline as a base - what yeilds can it give?

 

[G.Patton]

Try and figure out. Share us your research data. In theory, it's quite weak base and it would be not enough to eliminate -OH group.

 

[Kvadprime]

ok, I'll definitely write how everything went... I'm still waiting for my new labware to arrive

Thx

 

[rampage]

has anyone done the microwave version of this synthesis, curious as to the outcome?

 

[William D.]

This is an effective method. I irradiate at maximum power in short time intervals so that the mixture does not have time to boil.

 

[rampage]

that is the key, stopping the irradiation just prior or as soon as you see 1 tiny bubble rise up, did this method with very good success, simple but very effective. would be very interested if there's other synths that can be done using the microwave??

 

[William D.]

Stop when strong boiling begins. Yes, this is visible by bubbles. There are many different syntheses with MW, there are also on the forum. I think that ultrasound for p2np should also work well.