What is NEP like?

AntoineFranklin

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I am new here and Im sorry if general questions like this are unwelcome here. What I am asking in this thread is what NEP feels like. I know it's cathinone but I am asking is it like a-pvp/meth, primarily dopaminergic stim or is it like mdma/jeff/drone - an entactogen type stim?

Thanks in advance.
 

Paracelsus

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Greetings! Almost all questions are welcomed here :)

NEP is a synthetic cathinone, and its subjective effects typically fall somewhere between those of a primarily dopaminergic stimulant (like a-PVP or metha) and those of entactogenic stimulants (like MDMA or mephedrone). NEP primarily acts as a norepinephrine-dopamine reuptake inhibitor (NDRI), enhancing dopamine and norepinephrine availability in the brain. While it may have some serotonergic activity, it is weaker compared to serotonergic-heavy cathinones like mephedrone or MDMA.

NEP is known to produce a sense of euphoria, which is more reminiscent of substances like a-PVP or methamphetamine rather than the "lovey-dovey" feeling typical of MDMA or mephedrone. Users often report a strong boost in energy and focus, characteristic of dopaminergic stimulants. Similar to other cathinones, NEP has a high potential for compulsive redosing, linked to its rewarding dopaminergic activity.

While some users may feel a slight enhancement in sociability or empathy, it's usually not as profound or emotional as with MDMA or mephedrone. This aligns with NEP’s weaker serotonergic action. The physical sensations (e.g., body warmth or tingling) are present but tend to be more stimulant-like than the rushes or waves of bliss associated with entactogens.

As with many cathinones, NEP may cause vasoconstriction, increased heart rate, and sweating, similar to other potent stimulants. Due to its dopaminergic dominance, higher doses can produce anxiety, restlessness, or paranoia, aligning it more with drugs like a-PVP than MDMA.
 

pestax

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I couldn't have put it better myself
 

Jackalj

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Some people love it, some people hate it. From my personal experience it’s a lot of fun if you don’t overdo it. It feels very cardiotoxic in too high doses, if you do too much your heart will beat like fuck and you’ll sweat like a dog, in normal doses it’s a very nice meth/amph kinda high very productive and euphoria is definitely present. Fun to smoke in an oil burner too. Stay safe brother :)
 
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