Hello chemists. Is this method feasible?
Approximately 425 grams of ground ephedra plant material was washed three times with methanol. The methanol washings were collected and allowed to evaporate to produce a greenish-brown tar-like substance. To this material was added 250 mL of a 57% solution of hydriodic acid and 9.5 grams of red phosphorus in a 1000 mL round-bottom flask. The flask was equipped with a working condensor and a heating mantle. The mixture was heated and allowed to reflux for approximately 5 hours. The aqueous reaction solution was filtered, made basic with NaOH (pH>12), then extracted into trichlorotrifluoroethane (Freon-113). The organic solution was dried over anhydrous Na2SO4. Hydrogen chloride gas was then bubbled into the freon, resulting in the crystallization of the final product as the hydrochloride salt
Approximately 425 grams of ground ephedra plant material was washed three times with methanol. The methanol washings were collected and allowed to evaporate to produce a greenish-brown tar-like substance. To this material was added 250 mL of a 57% solution of hydriodic acid and 9.5 grams of red phosphorus in a 1000 mL round-bottom flask. The flask was equipped with a working condensor and a heating mantle. The mixture was heated and allowed to reflux for approximately 5 hours. The aqueous reaction solution was filtered, made basic with NaOH (pH>12), then extracted into trichlorotrifluoroethane (Freon-113). The organic solution was dried over anhydrous Na2SO4. Hydrogen chloride gas was then bubbled into the freon, resulting in the crystallization of the final product as the hydrochloride salt
