Someone has any experience with 4-Methoxy Phenyl Acetone?

[btcboss2022]

I found access to an interesting product:

4-Methoxy Phenyl Acetone​

But still not sure if it could be useful, someone has any experience with it?

Thanks.

 

[WillD]

You can make good pills from this. If there is this substance, I can help with synthesis.

 

[MadHatter]

I'm sorry, is this a psychoactive substance?

 

[btcboss2022]

I think no, theoretically should be a precursor very similar chemically to Phenylacetone(P2P) but I'm not completely sure if it works or how.

 

[MadHatter]

Ok, yes, I got confused by the mention of pills. It's basically P2P with a methoxy group on it. But removing methoxy groups is, as I understand, not very easy. It involves demethylation, removing a carbon, and it's generally a toxic and complicated business. Also, in this case, it would need to be very selective, so you don't touch the other parts of the molecule.

Interesting to hear what the experts have to say though!

 

[ADATA]

You can only Wikipedia
cathinone derivatives
there are hundreds
not necessarily popular

 

[ADATA]

Can be brominated and then aminated like 4MMC

 

[WillD]

Impossible. Only 4-methoxy product and all.

 

[btcboss2022]

Clemmensen reaction with HI+P4 woudn't works?

4-methoxy-phenylacetone->HI+P4->4-hydroxy-phenylacetone->NaSO4 hydrolysis->phenylacetone

I'm wrong?

Another option could be demethylation using BBr3.

Thanks.

 

[btcboss2022]

So, 4-methoxy meth, 4-methoxy amphetamine...right?
Will be so much different in the effects these products in comparison with the original ones?

 

[WillD]

Yes, the difference is big. The first is more of a stimulant, 4-methoxy euphoric. It is best taken in the form of capsules and tablets.

 

[HerrHaber]

PMA or 4MeO-amphetamine is the one I had success with my first time and I ended up intoxicated but my only advice is that you should be careful. Otherwise the carbonyl can be also obtained from anethole (4-MeO-allylbenzene).

 

[Sue]

"Yes can be used in place of P2P in any synthesis to amphetamine. The end result will be 4 methoxy-amphetaimine "PMA" for short. Look it up lots of references and info about it. Made some back in the mid 80's and N-methylated half of it....