PHENIBUT
Phenibut can be synthesized from the reaction between β-phenyl-GABA and hydrochloric acid. The synthesis process involves the following steps:
The complete synthesis reaction can be represented as follows:
Phenylacetyl chloride + Glycine --> β-phenyl-GABA
β-phenyl-GABA + PCl3 --> β-phenyl-γ-aminobutyryl chloride
β-phenyl-γ-aminobutyryl chloride + NaOH --> Phenibut
Please note that this is an advanced synthesis and should only be performed by trained professionals with proper safety equipment and protocols.
Phenibut can be synthesized from the reaction between β-phenyl-GABA and hydrochloric acid. The synthesis process involves the following steps:
- Acylation of glycine with phenylacetyl chloride: In this step, glycine is reacted with phenylacetyl chloride in the presence of an organic base such as triethylamine to yield β-phenyl-GABA.
- Cyclization of β-phenyl-GABA: The β-phenyl-GABA is then reacted with phosphoryl chloride to form β-phenyl-γ-aminobutyryl chloride. This is then reacted with sodium hydroxide to form the final product, Phenibut.
The complete synthesis reaction can be represented as follows:
Phenylacetyl chloride + Glycine --> β-phenyl-GABA
β-phenyl-GABA + PCl3 --> β-phenyl-γ-aminobutyryl chloride
β-phenyl-γ-aminobutyryl chloride + NaOH --> Phenibut
Please note that this is an advanced synthesis and should only be performed by trained professionals with proper safety equipment and protocols.
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