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MXE

The Alchemist

Don't buy from me
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Good Evening Everyone
I've collected the following resources to open discussion on the synthesis of 3-MeO-2'-oxo-PCE aka Methoxetamine or MXE.


I've lifted the following comment from reddit, courtesy of the users there: https://www.reddit.com/r/TheeHive/comments/mfd5mp/_/gspzftu /


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And in case it ever goes down (in reference to a DEA document on synthesis of MXE):
https://web.archive.org/web/2020102...les/pr/microgram-journals/2012/mj9-1_3-17.pdf


Some more resources here as well:


A Multi-Disciplinary MXE Analysis by Vortech (RIP) has a chapter on the chemistry
UK Gov't Report has some chemistry info: https://assets.publishing.service.g...chment_data/file/119087/methoxetamine2012.pdf
WHO report as well: https://www.who.int/medicines/areas/quality_safety/4_22_review.pdf
And some past threads on it with lots of valuable info on difficult individual subprocesses in the synth:


/r/TheeHive/comments/9yoguq/mxe_total_synthesis/
/r/TheeHive/comments/iposiu/a_total_synthesis_of_mxe_otc/
/r/TheeHive/comments/9x3gh8/another_theoretical_mxe_synthesis/
/r/TheeHive/comments/j90agw/mxe_synthesis_again_new_route/
/r/TheeHive/comments/9w97qg/synthesis_of_methoxetamine_and_other/
/r/researchchemicals/comments/99efk5/feasibility_of_synthesizing_mxe/
/r/TheeHive/comments/9gb5jr/mxe_synthesis/
/r/TheeHive/comments/hhk93s/alternative_synthesis_routes_for_mxe_copied_from/
/r/DrugNerds/comments/104r3f/methoxetamine_synthesis/
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A potential route is presented as follows:
https://pastebin.com/ed9r9VnP


Which is similar to the one posted here:


I like this method to produce Methoxetamine, but I just wish we can open discussion further! What can be replaced with this and that, how can we alter the formula, etc.
 
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