Best CBD isomerization to Delta 9?

[Latin King]

Anyone know what best way is to get at least 80% cbd isomerization to at least 80% D9?
What acid and NPS works best for high D9 yield?

thanks friends

 

[thch]

Best yield is TIBA, friend.

If you aren't comfortable handling pyrophorics I suggest getting comfortable with Zeolite and PTSA as it's quite easy to make large scale batches very quickly, even solventlessly if you don't mind eating it.

 

[Latin King]

TIBA is impossible for me to get and its a bit too dangerous LOL
The zeolite method is like the citric acid method good for some home cooking but not recommend for large scale. there are easier ways to get high d9 yields but people dont share them

 

[PharmacopeiaLabs]

amberlyst 15 beads.

 

[cake]

I prefer 4A Zeolite Molecular Sieves — better ∆9 selectivity.

 

[PharmacopeiaLabs]

Do you have info on molecular sieves? we can exchange information if you want.

 

[cake]

US Patent for Method for the preparation of dronabinol Patent (Patent # 8,324,408 issued December 4, 2012) - Justia Patents Search

The present invention relates to a method for the preparation of dronabinol ((6aR-trans)-6a,7,8,10a-tetrahydro-6,6,9-trimethyl-3-pentyl-6H-dibenzo[b,d]pyran-1-ol, Δ9-tetrahydrocannabinol (Δ9-THC)) from cannabidiol (CBD) by cyclization of cannabidiol (CBD)...

patents.justia.com