Starting reagents and materials
100 ml H2O
7.21 g THF
15.1 g KBrO3
13.6 g KHSO4
14 g Na2S2O5 dissolved in 150 ml H2O
150 ml H2O
250-300 ml DCM
50 g Na2SO4
3.38 g NaHCO3 dissolved in 15 ml H2O
3-neck flask 1000 ml
Thermometer
High efficiency double circuit reflux
Magnetic stirrer
Cold...
Introduction.
This file deals with the synthesis of GHB and related compounds. It is highly dangerous to attempt a synthesis of GHB without the proper knowledge of practical organic chemistry. The far most simple way to produce GHB is by the hydrolysis of the corresponding lactone (a cyclic...