In the history of mankind, there have been several waves of free circulation of narcotic substances. Imagine that LSD and MDMA were once legal, during the psychedelic revolution. Substances were freely distributed before they were banned. But the most striking example of the turnover of research chemicals was from 2007 to 2015, when John W. Huffman discovered a new class of cannabinoids with a new chemical structure.
And now, on the threshold of 2025, many are wondering if there are still unknown new legal drugs? Of course, it all depends on the regulatory authorities. Many countries have introduced the concept of analogue and learned to conduct research on rats in order to equate large quantities of seized substances with prohibited ones.
But African countries, I am sure, do not know how to do this, and they limit themselves to the list of prohibited substances of the International Committee on Drugs. There are a lot of gaps in this list, and there is something to pay attention to.
Human receptors are designed in such a way that there are a lot of options for action, especially on cannabinoid and opiate receptors. Perhaps there are an infinite number of chemical compounds that can have a psychoactive effect. And we will definitely see more discoveries.
Pharmaceutical companies are not interested in developing psychoactive substances because it is prohibited by law. This may be of interest to underground dealers in order to avoid criminal responsibility, as well as to reduce the risks of their buyers. But such dealers are not ready to invest in drug design, for many it will not pay off. Moreover, if a substance gains popularity, it will be quickly banned.
Now the entire design of drugs is reduced to primitive analogues, for example, to make 2-fluoro-amphetamine from amphetamine. It is simple, and in some cases helps to avoid criminal risks. And even sometimes the psychoactive effect changes for the better, but more often on the contrary, the design leads to a deterioration in the properties of substances.
I know a lot of potentially interesting substances, some could turn the market upside down. But, unfortunately, I am not ready to do serious research now.
And now, on the threshold of 2025, many are wondering if there are still unknown new legal drugs? Of course, it all depends on the regulatory authorities. Many countries have introduced the concept of analogue and learned to conduct research on rats in order to equate large quantities of seized substances with prohibited ones.
But African countries, I am sure, do not know how to do this, and they limit themselves to the list of prohibited substances of the International Committee on Drugs. There are a lot of gaps in this list, and there is something to pay attention to.
Human receptors are designed in such a way that there are a lot of options for action, especially on cannabinoid and opiate receptors. Perhaps there are an infinite number of chemical compounds that can have a psychoactive effect. And we will definitely see more discoveries.
Pharmaceutical companies are not interested in developing psychoactive substances because it is prohibited by law. This may be of interest to underground dealers in order to avoid criminal responsibility, as well as to reduce the risks of their buyers. But such dealers are not ready to invest in drug design, for many it will not pay off. Moreover, if a substance gains popularity, it will be quickly banned.
Now the entire design of drugs is reduced to primitive analogues, for example, to make 2-fluoro-amphetamine from amphetamine. It is simple, and in some cases helps to avoid criminal risks. And even sometimes the psychoactive effect changes for the better, but more often on the contrary, the design leads to a deterioration in the properties of substances.
I know a lot of potentially interesting substances, some could turn the market upside down. But, unfortunately, I am not ready to do serious research now.
